Can You Take Jardiance for Weight Loss? What the Research Says

Can You Take Jardiance for Weight Loss? What the Research Says

Jardiance (empagliflozin) is best known for treating Type 2 diabetes and heart failure, but many patients have noticed an additional unexpected benefit: weight loss. If you’re wondering whether Jardiance could help you lose weight—and how it compares to dedicated weight loss treatments—this guide will explain everything you need to know.

We’ll cover what the studies say, realistic expectations for weight loss, and how Americans can save significantly on Jardiance by ordering from Canada through trusted prescription referral services like Over the Border Meds.

What Is Jardiance?

Jardiance belongs to a class of medications called SGLT2 inhibitors. These drugs work by:

  • Blocking the SGLT2 protein in the kidneys

  • Preventing reabsorption of glucose into the bloodstream

  • Helping the body eliminate excess sugar through urine

As a result, Jardiance lowers blood sugar levels in patients with Type 2 diabetes. More recently, Jardiance has also been approved to treat heart failure in patients with or without diabetes, thanks to its ability to reduce hospitalizations and improve survival.

How Does Jardiance Cause Weight Loss?

 

The weight loss seen with Jardiance is an indirect effect of how the medication works:

  • When your body excretes glucose (sugar) through urine, it loses calories

  • Jardiance can cause patients to lose 200–300 calories per day through urinary glucose loss

  • Over time, this calorie loss can lead to modest weight loss

Additionally, by lowering blood sugar, Jardiance may improve insulin sensitivity, which can also help with weight control.

However, it’s important to understand that Jardiance is not officially approved for weight loss, and the amount of weight loss tends to be more modest compared to medications like Wegovy (semaglutide) or Mounjaro (tirzepatide).

What Does the Research Say About Jardiance and Weight Loss?

 

Clinical studies have consistently shown mild to moderate weight loss in patients using Jardiance:

  • Average weight loss is about 2% to 3% of baseline body weight

  • Patients without significant dietary changes typically lose 5 to 8 pounds over several months

  • Patients who combine Jardiance with healthy eating and exercise can sometimes see greater reductions

In the EMPA-REG OUTCOME trial (a major study on Jardiance’s heart benefits), participants lost an average of about 2 kg (4.4 pounds) over 12 weeks compared to placebo.

In combination with Metformin (a common Type 2 diabetes medication), weight loss was slightly greater.

How Does Jardiance Compare to Other Weight Loss Medications?

 

Compared to GLP-1 agonists like Ozempic, Wegovy, or Mounjaro, Jardiance offers less dramatic weight loss.

MedicationAverage Weight Loss
Jardiance5–8 pounds
Ozempic12–15% of body weight
Wegovy15%+ of body weight
Mounjaro20%+ of body weight
 

That said, Jardiance might be a good starting point for patients who:

  • Want both diabetes and heart failure benefits

  • Prefer oral medications (Jardiance is a once-daily tablet)

  • Are looking for modest weight loss without injections

Who Might Benefit from Jardiance for Weight Loss?

 

Jardiance may be a good option for:

  • Patients with Type 2 diabetes who need better blood sugar control

  • Patients with heart failure needing cardiovascular protection

  • Patients looking for a little extra weight loss without adding a second medication

  • People who are not ready or eligible for GLP-1 therapy

It’s important to note that Jardiance should not replace proper diet and exercise. And while weight loss is a nice side effect, the primary goal remains blood sugar and heart health management.

How to Save Money on Jardiance: Order from Canada

 

The cost of Jardiance in the United States can be high, especially without insurance coverage. Many Americans are finding relief by ordering Jardiance from Canada through trusted services like Over the Border Meds.

MedicationU.S. Price (avg)Over the Border Meds (Canada)
Jardiance 10 mg (30 tabs)~$650~$109 USD
Jardiance 25 mg (30 tabs)~$700~$125 USD

 

That’s up to 80% savings!

Ordering is simple:

  • Upload your valid U.S. prescription

  • Choose your preferred strength (10 mg or 25 mg)

  • Enjoy discreet delivery directly to your home

Use coupon code Hello10 to save an additional 10% on your first order.

Important Safety Tips

 

If you’re considering Jardiance for weight loss, remember:

  • It’s prescribed primarily for diabetes and heart failure, not as a standalone weight loss drug

  • Common side effects include urinary tract infections, yeast infections, and dehydration

  • Drink plenty of water and monitor for signs of infection

  • Always work with your healthcare provider when adjusting medications

Final Thoughts

 

While Jardiance is not a weight loss drug, it can offer modest weight reduction for patients already taking it for diabetes or heart health. Combined with healthier lifestyle habits, it can be an excellent choice for those needing multiple health benefits in one medication.

If you’re interested in starting or continuing Jardiance—and saving hundreds of dollars while you’re at it—consider ordering safely from Canada through Over the Border Meds. It’s an affordable, convenient way to access essential medications for better health.

📌 Learn more and start your order at Over the Border Meds.