Trulicity (Dulaglutide) Injection

What is Trulicity?

Trulicity is a once-weekly injection used to improve blood sugar control in adults with type 2 diabetes. It belongs to a class of medications known as GLP-1 receptor agonists, which help regulate blood sugar levels and may aid in weight management. Trulicity is often prescribed alongside diet and exercise to reduce the risk of cardiovascular events in patients with diabetes.

How Trulicity Works

Trulicity mimics the natural GLP-1 hormone, which helps the pancreas release insulin when blood sugar levels are high. It also slows stomach emptying, reducing post-meal blood sugar spikes, and decreases glucagon, a hormone that raises blood sugar levels. These mechanisms help maintain stable blood sugar levels throughout the day.

Trulicity Dosage and Administration

Trulicity is available in prefilled pens with doses of 0.75 mg, 1.5 mg, 3 mg, and 4.5 mg, administered once a week by subcutaneous injection in the abdomen, thigh, or upper arm. The starting dose is typically 0.75 mg, with gradual increases based on your healthcare provider’s recommendations to optimize blood sugar control.

Trulicity should not be mixed with insulin or injected at the same site as other medications. If you miss a dose, administer it as soon as possible, provided there are at least 3 days (72 hours) before the next scheduled dose.

Possible Side Effects of Trulicity

Common side effects include:

• Nausea
• Diarrhea
• Abdominal pain
• Decreased appetite
• Fatigue

Severe but rare side effects include pancreatitis, thyroid tumors, and severe allergic reactions. Contact your healthcare provider immediately if you experience persistent abdominal pain, difficulty swallowing, or swelling of the face or throat.

Precautions When Using Trulicity

Before starting Trulicity, inform your healthcare provider if you have:

• A personal or family history of thyroid cancer
• Severe gastrointestinal issues
• Kidney or liver problems
• Heart conditions

Trulicity is contraindicated in patients with a history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2).

Buying Trulicity from Canada

Buying Trulicity from Canada can offer significant savings for U.S. patients. Canadian pharmacies often provide more affordable pricing due to strict regulations on medication costs. Here’s how to safely purchase Trulicity from Canada:

• Check Licensing: Ensure the pharmacy is licensed and reputable.
• Consult Your Doctor: Discuss your plan with your healthcare provider to ensure it’s appropriate.
• Provide a Valid Prescription: A U.S. prescription is required to order Trulicity from Canada.
• Understand Import Rules: The FDA allows a 90-day supply of medication for personal use.

Storage Instructions for Trulicity

Store Trulicity pens in the refrigerator between 2°C and 8°C (36°F to 46°F). Trulicity pens can be kept unrefrigerated for up to 14 days at temperatures not exceeding 30°C (86°F). Avoid freezing the pens and protect them from direct sunlight.

Frequently Asked Questions (FAQs)

Is Trulicity used for weight loss?

While Trulicity is primarily prescribed for type 2 diabetes, many patients experience weight loss as a secondary benefit due to its appetite-suppressing effects.

Is there a generic version of Trulicity?

No, Trulicity does not currently have a generic version. However, buying Trulicity from Canada may offer substantial savings compared to U.S. prices.

Can Trulicity be used with other diabetes medications?

Yes, Trulicity is often used in combination with other diabetes medications, such as metformin or basal insulin. Your doctor may adjust dosages to minimize the risk of hypoglycemia.

For more information, consult your healthcare provider or refer to the full product monograph here.

It is given as a subcutaneous (under the skin) injection once a week. It comes in a pre-filled pen that is ready to use. No mixing is required. You can inject Trulicity in the abdomen, thigh, or upper arm. Rotate injection sites and avoid injecting into the same spot each week. Always use a new needle for each injection and dispose of it properly.