Pradaxa (Dabigatran Etexilate) Capsules

What is Pradaxa?

Pradaxa (Dabigatran Etexilate) is an anticoagulant medication used to reduce the risk of stroke and blood clots in patients with non-valvular atrial fibrillation. It is also prescribed for the prevention of venous thromboembolism (VTE) following hip or knee replacement surgery, as well as for the treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE). Pradaxa works by inhibiting thrombin, a key enzyme in the blood clotting process.

How Pradaxa Works

Pradaxa prevents the formation of blood clots by inhibiting thrombin, a key enzyme in the clotting process. By blocking the action of thrombin, Pradaxa helps prevent the development of blood clots in the veins and arteries. This makes it an effective medication for reducing the risk of stroke in patients with atrial fibrillation and for treating conditions like DVT and PE.

Pradaxa Dosage and Administration

Pradaxa is available in capsule form in strengths of 75 mg, 110 mg, and 150 mg. The dosage depends on the condition being treated and the patient's kidney function. For patients with atrial fibrillation, the typical dose is 150 mg twice daily. For patients who have undergone hip or knee replacement surgery, the usual dose is 110 mg once daily on the first day, followed by 220 mg once daily. For DVT and PE treatment, 150 mg twice daily is the standard dose.

It is important to follow your healthcare provider’s instructions carefully when taking Pradaxa. Do not stop taking this medication without consulting your healthcare provider, as stopping suddenly may increase the risk of a stroke or blood clot.

Possible Side Effects of Pradaxa

Common side effects of Pradaxa include:

• Bleeding (including bruising, nosebleeds, and heavy menstrual periods)
• Indigestion
• Stomach pain
• Nausea

Serious side effects may include:

• Severe bleeding (blood in urine, stool, or coughing up blood)
• Allergic reactions (swelling of the face, lips, tongue, or throat)
• Severe liver problems (yellowing of the skin or eyes)

If you experience severe side effects, contact your healthcare provider immediately. Pradaxa increases the risk of bleeding, so it is important to monitor for any signs of unusual bleeding.

Drug Interactions

Pradaxa may interact with other medications, including:

• Other anticoagulants (warfarin, heparin)
• Nonsteroidal anti-inflammatory drugs (NSAIDs)
• Antiplatelet agents (aspirin, clopidogrel)
• P-glycoprotein inhibitors (amiodarone, dronedarone)

Always inform your healthcare provider of any medications, supplements, or herbal products you are taking before starting Pradaxa to avoid potential interactions.

Precautions When Using Pradaxa

Before starting Pradaxa, inform your healthcare provider if you have a history of:

• Bleeding disorders
• Kidney or liver problems
• Recent surgery or trauma
• Pregnancy or breastfeeding

Pradaxa may not be suitable for patients with certain medical conditions, and adjustments may be necessary based on individual risk factors.

Buying Pradaxa from Canada

U.S. patients looking to save on Pradaxa can consider buying from Canada, where prescription medications are often available at a lower cost. Here’s how to safely purchase Pradaxa from Canada:

• Check Pharmacy Accreditation: Ensure the Canadian pharmacy is licensed and reputable.
• Consult Your Doctor: Discuss with your healthcare provider whether purchasing from Canada is a safe and appropriate option for you.
• FDA Rules: U.S. patients can import up to a 90-day supply of medication for personal use under FDA guidelines.
• Valid Prescription: You will need a valid U.S. prescription to buy Pradaxa from Canada.

Buying Pradaxa from Canada can be a cost-effective option for U.S. patients. Be sure to only purchase from legitimate online Canadian pharmacies to avoid counterfeit products.

Storage Instructions for Pradaxa

Store Pradaxa capsules in their original packaging to protect them from moisture. Keep the capsules at room temperature, between 15°C and 30°C (59°F and 86°F), and away from heat and direct light. Make sure to keep the medication out of reach of children and pets.

Frequently Asked Questions (FAQs)

Is Pradaxa a blood thinner?

Yes, Pradaxa is an anticoagulant or blood thinner that helps prevent the formation of blood clots by inhibiting thrombin, a key enzyme in the clotting process.

Can I buy Pradaxa from Canada without a prescription?

No, a valid prescription is required to purchase Pradaxa from a Canadian pharmacy. You can use a U.S. prescription to legally buy Pradaxa from Canada.

Is there a generic version of Pradaxa?

Yes, there is a generic version of Pradaxa available in Canada, which can help you save more. Many U.S. patients choose to buy the generic form from Canadian pharmacies to reduce their prescription costs. Be sure to ask your healthcare provider about generic options when considering your anticoagulant treatment.

For more detailed information, you can refer to the official product monograph here.

Pradaxa is typically taken orally, usually twice a day, as prescribed by your doctor. Swallow the capsule whole with a full glass of water, and avoid crushing, chewing, or opening the capsules. Be sure to take it at the same time each day to maintain consistent levels in your body.