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Eliquis (Apixaban)
Eliquis (Apixaban) 
Apixaban
Product information
Eliquis (apixaban) is an oral anticoagulant used to reduce the risk of stroke and blood clots in people with atrial fibrillation, as well as to treat and prevent deep vein thrombosis (DVT) and pulmonary embolism (PE). It works by inhibiting factor Xa, an important protein involved in clot formation. When taken as prescribed, Eliquis helps lower the risk of serious clot-related complications.
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Eliquis (Apixaban): Uses, Dosing, Side Effects & How It Works
Eliquis (apixaban) is a direct oral anticoagulant (DOAC) that helps prevent harmful blood clots by selectively inhibiting Factor Xa. This lowers the risk of stroke in atrial fibrillation (AFib) and treats or prevents clots in the veins and lungs.
What Eliquis Is Used For
- Stroke/systemic embolism prevention in nonvalvular AFib
- Treatment of DVT (deep vein thrombosis) and PE (pulmonary embolism)
- Prevention of recurrent DVT/PE after initial therapy
- Post–hip or knee replacement prophylaxis to prevent clots
For full prescribing details, see the official Eliquis Product Monograph (Bristol Myers Squibb Canada).
Dosing (General Information)
Dosing is individualized by your prescriber based on your indication, age, kidney function, weight, and other medicines. Follow your prescription exactly. If you have difficulty swallowing, tablets may be crushed and mixed with water or applesauce as directed by your clinician.
Missed dose: Take it when remembered. If it’s close to the next dose, skip the missed dose—do not double up.
Available Doses of Eliquis (Apixaban)
Eliquis (apixaban) is available in multiple tablet strengths to help meet each patient’s medical needs. Your prescriber will determine the right dosage based on your condition, age, kidney function, and other medications you may be taking. In most cases, treatment starts at a standard dose and may be adjusted over time.
- 2.5 mg tablets: Often used for patients with reduced kidney function or those who require lower dosing after surgery.
- 5 mg tablets: Commonly prescribed for the prevention of stroke and blood clots in patients with atrial fibrillation or for treating DVT/PE.
Each tablet can be taken with or without food, and it’s recommended to take Eliquis around the same time every day for best results. Always follow your prescriber’s instructions and do not change your dose without consulting your healthcare provider.
Common Side Effects
Like all blood thinners, Eliquis can increase bleeding risk. Common effects include:
- Easy bruising; gum or nosebleeds
- Prolonged bleeding from cuts
- Fatigue or weakness (possible anemia)
Seek urgent care for severe or uncontrollable bleeding, black/tarry stools, red/brown urine, coughing/vomiting blood, sudden severe headache, fainting, or stroke symptoms.
Who Should Not Take Eliquis
- Active bleeding or conditions with high bleeding risk
- Severe liver disease
- Allergy to apixaban or any tablet ingredient
- Use with certain interacting medicines (e.g., strong CYP3A4/P-gp inhibitors like ketoconazole or inducers like rifampin)—ask your prescriber
How Eliquis Works
Apixaban selectively inhibits Factor Xa, a key enzyme in the coagulation cascade. By reducing thrombin generation and clot formation, it helps protect against stroke in AFib and treats/prevents venous thromboembolism (VTE).
More Clinical Details
Pregnancy & Breastfeeding
Eliquis is not recommended during pregnancy due to limited human data and bleeding risk. If anticoagulation is needed during pregnancy, clinicians may consider low-molecular-weight heparin (LMWH). Because apixaban may be present in breast milk, avoid use while breastfeeding unless your prescriber advises otherwise.
Drug, Food & Alcohol Interactions
- Medicines: NSAIDs (e.g., ibuprofen), other anticoagulants/antiplatelets, and some antidepressants (SSRIs/SNRIs) can raise bleeding risk.
- Food: Avoid grapefruit/grapefruit juice (interaction potential).
- Alcohol: May increase bleeding risk—ask your prescriber about safe limits.
Monitoring & Procedures
Your prescriber may check kidney/liver function as appropriate. You may need to pause Eliquis before surgery or dental work—only under medical guidance.
Eliquis Alternatives & Generic Options
- Generic apixaban (Eliquis): Same active ingredient; usually lower cost.
- Rivaroxaban (Xarelto) / generic rivaroxaban: Factor Xa inhibitor, often once daily.
- Dabigatran (Pradaxa): Direct thrombin inhibitor (capsules).
- Edoxaban (Savaysa): Another oral Factor Xa inhibitor.
- Warfarin: Inexpensive but requires INR monitoring and dietary consistency.
Lower Your Cost (For U.S. Patients)
If Eliquis is too expensive locally, Americans can order brand Eliquis or generic apixaban from Canada for personal use with a valid U.S. prescription. Pricing starts around $70.95 for 60 tablets (strength-dependent), and new customers can use code Hello10 for 10% off the first order. Orders typically ship to U.S. residential addresses as a 90-day personal-use supply. Prices checked October 17, 2025.
Save even more: See how a 3-month supply can reduce your per-tablet cost: Buy More Apixaban, Save More.
How to Buy from Canada (Step-by-Step)
- Get a valid U.S. prescription for Eliquis (apixaban).
- Send your prescription: Your clinic can fax to 1-833-209-3704 or you can upload your prescription.
- Choose brand or generic: Select Eliquis or generic apixaban and the correct tablet strength (2.5 mg or 5 mg).
- Apply your coupon: Use Hello10 for 10% off your first order.
- Shipping: Orders ship to U.S. residential addresses (typically within 1–2 weeks), up to a 90-day supply.
When to Seek Medical Help
- Severe or uncontrolled bleeding
- Signs of stroke (sudden weakness, facial droop, trouble speaking, severe headache)
- Black/tarry stools or red/brown urine
- Any unusual or concerning symptoms
References
Official monograph and full product information: Eliquis Product Monograph (Bristol Myers Squibb Canada).
Disclaimer: This page is for educational purposes and does not replace medical advice. Always consult your healthcare provider before starting or changing medications.
Ready to order? Start here: Buy Eliquis from Canada
Legal and Safety Information
Information on this page is provided for general educational purposes and should not replace advice from a licensed healthcare professional. Some U.S. patients choose to source medications like Eliquis or generic apixaban through licensed Canadian prescription referral services to help reduce costs. Medications dispensed by Canadian pharmacies are Health Canada–approved and intended for personal use only. Always follow your prescriber’s instructions and consult your healthcare provider with any questions about your treatment.
