Can I Take Jardiance with Metformin? What You Should Know

Can I Take Jardiance with Metformin? What You Should Know

f you’re managing Type 2 diabetes, your doctor may prescribe both Jardiance and Metformin. These two medications work in different ways to lower blood sugar levels and can be safely taken together for better control of your diabetes. In fact, combining Jardiance with Metformin is a common and effective treatment strategy.

In this article, we’ll answer some of the most frequently asked questions about taking Jardiance with Metformin, including the best time of day to take them, whether they should be taken with food, what side effects to expect, and whether they are available as a combination pill.

What Are Jardiance and Metformin?

  • Metformin is often the first-line treatment for Type 2 diabetes. It works by reducing glucose production in the liver and improving how your body uses insulin.

  • Jardiance (empagliflozin) is part of a newer class of medications called SGLT2 inhibitors, which help your body get rid of excess glucose through your urine.

When taken together, Jardiance and Metformin can help: ✅ Lower your A1C
✅ Improve insulin sensitivity
✅ Promote modest weight loss
✅ Lower the risk of heart and kidney complications in some patients

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Best Time of Day to Take Jardiance with Metformin

 

There isn’t a single “best” time of day that works for everyone, but here are some general guidelines:

  • Jardiance is usually taken once daily in the morning, with or without food.

  • Metformin is typically taken once or twice a day (morning and/or evening), depending on the dose and formulation (immediate vs. extended release).

💡 Tip: Many patients find it helpful to take both medications with their breakfast to maintain consistency and reduce stomach upset from Metformin.

Always follow your doctor’s instructions, as individual recommendations can vary based on your health status and blood sugar levels.

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Should I Take Jardiance and Metformin with Food?

 

  • Metformin should always be taken with food, as it can cause stomach upset, nausea, or diarrhea when taken on an empty stomach.

  • Jardiance can be taken with or without food, but taking it with food may help reduce the risk of nausea for some people.

For convenience and better tolerance, many people take both Jardiance and Metformin with breakfast or the largest meal of the day.

What Side Effects to Expect When Taking Jardiance with Metformin

 

Combining these medications may slightly increase the chances of side effects, but most people tolerate the combo well.

Common Side Effects of Metformin

  • Nausea

  • Diarrhea

  • Gas or bloating

  • Metallic taste in the mouth

  • Stomach pain

Common Side Effects of Jardiance

  • Increased urination

  • Thirst

  • Genital yeast infections (especially in women)

  • Urinary tract infections

Rare but Serious Risks

  • Dehydration – Jardiance can lead to more fluid loss

  • Lactic acidosis – A rare but serious side effect linked to Metformin

  • Ketoacidosis – Rare but possible with SGLT2 inhibitors like Jardiance

  • Low blood sugar (hypoglycemia) – More likely if you’re on insulin or sulfonylureas

If you’re starting both medications together, your doctor may start you on a lower dose and monitor your blood sugar and side effects closely.

Do Jardiance and Metformin Come in a Combo Pill?

 

Yes! For added convenience, there is a combination pill that contains both Jardiance and Metformin. It’s called:

💊 Synjardy

Synjardy is available in different strengths and comes in tablet form, combining:

  • Empagliflozin (Jardiance) 5 or 12.5 mg

  • Metformin 500, 850, or 1000 mg

It can be taken once or twice daily, depending on your doctor’s recommendation.

💡 Combo pills like Synjardy can simplify your routine and improve medication adherence.

Can I Save Money by Ordering Jardiance or Synjardy from Canada?

 

Absolutely! Prescription medications like Jardiance, Synjardy, and Metformin are often significantly cheaper when ordered through a Canadian prescription referral service like Over the Border Meds.

Here’s why U.S. patients choose to order from Canada:

✅ Up to 60% lower prices
✅ Brand-name and generic options available
✅ No insurance required
✅ Easy online ordering with a valid U.S. prescription
✅ Home delivery to your door

If you’ve been prescribed Jardiance with Metformin and are looking for affordable options, Over the Border Meds can help you access safe, cost-effective medications from licensed Canadian pharmacies.

Final Thoughts: Taking Jardiance with Metformin

 

Yes, you can take Jardiance with Metformin, and the combination is often recommended for better blood sugar control and added health benefits.

Here’s what to remember:

  • Take Metformin with food, preferably in the morning

  • Take Jardiance in the morning, with or without food

  • Monitor your body for side effects

  • Consider Synjardy if you’d prefer a combination pill

  • Look into cost-saving options by ordering from Canada through Over the Border Meds

If you have any concerns, always talk to your healthcare provider before starting or switching medications.

📌 Learn more about affordable options for Jardiance and Synjardy at Over the Border Meds