How to Reduce the Cost of Eliquis Without Splitting Tablets

How to Reduce the Cost of Eliquis Without Splitting Tablets

Eliquis (apixaban) is a widely prescribed blood thinner used to prevent stroke, deep vein thrombosis (DVT), and pulmonary embolism (PE). But for many Americans without insurance or with high copays, the cost of Eliquis can be difficult to manage.

Some patients consider splitting their tablets—especially the 5 mg strength—in an attempt to stretch their supply or mimic the lower 2.5 mg dose. While this may seem like a simple cost-cutting strategy, splitting Eliquis tablets is not recommended. Fortunately, there are safer and more effective ways to reduce your out-of-pocket cost

Why Eliquis Tablets Should Not Be Split

Eliquis tablets are film-coated and not scored, meaning they are not designed to be cut in half. Splitting them can lead to:

  • Uneven dosing: You may get more or less than the intended dose
  • Reduced effectiveness: The medication may not be absorbed properly
  • Increased risk: Inconsistent dosing can raise your risk of blood clots or bleeding

Apixaban works by maintaining steady levels in the bloodstream. Any variation can reduce the protection it provides. Manufacturers and healthcare professionals strongly advise against cutting or crushing Eliquis tablets for dose adjustment or savings.

Common Reasons Patients Consider Splitting

Despite these risks, many patients consider splitting tablets due to:

  • Cost savings: Assuming 5 mg and 2.5 mg tablets are priced similarly
  • Availability issues: Only one strength may be in stock
  • Delaying refills: Trying to extend a limited supply

While understandable, these reasons should not outweigh the safety risks involved in altering prescribed medication.

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Safer Ways to Reduce the Cost of Eliquis

If you’re paying out of pocket or struggling with insurance coverage, there are safer options that don’t involve splitting tablets:

Ask for the Correct Dose

If you’ve been prescribed 2.5 mg twice daily, your doctor can write a prescription specifically for the 2.5 mg strength. This avoids any need for cutting tablets and ensures you’re taking the correct amount.

Consider Generic Apixaban

In Canada, generic apixaban is available at significantly lower prices than brand-name Eliquis in the U.S. Both the 2.5 mg and 5 mg strengths are commonly available through Canadian pharmacies.

Order Through a Canadian Prescription Referral Service

Over the Border Meds connects Americans with licensed Canadian pharmacies offering lower prices on both brand and generic medications. With a valid U.S. prescription, you can order a 2.5 mg or 5 mg strength directly—no tablet splitting required.

Average Canadian pricing (as of 2025):

  • Apixaban 2.5 mg or 5 mg: $72 for a 30-day supply
  • Shipping available across the U.S. for personal use
  • 3-month supply options help reduce per-dose cost

Upload your prescription here:
https://overthebordermeds.com/upload-prescription-document/

eliquis tablets should not be cut or crushed to save money

What About Crushing Eliquis?

Crushing Eliquis tablets is not a safe way to reduce costs or split doses. While it may seem like an alternative to splitting, it carries similar risks—inaccurate dosing, reduced absorption, and increased risk of side effects.

Crushing is sometimes allowed for patients with swallowing difficulties, but only under medical supervision. In these cases, the crushed tablet may be mixed with water or applesauce and taken right away. This is a clinical workaround—not a cost-saving method.

Unless advised by your doctor, you should not crush or alter Eliquis. If cost is a concern, the safer approach is to ask your provider about prescribing the correct strength or ordering the medication through a trusted Canadian pharmacy at a lower price.

Frequently Asked Questions

Can I split Eliquis 5 mg tablets in half to make a 2.5 mg dose?
No. Eliquis tablets are not scored, and splitting may lead to inaccurate dosing.

Is generic apixaban the same as Eliquis?
Yes. Generic apixaban contains the same active ingredient and works the same way. In Canada, it’s available at a much lower cost.

How much can I save by ordering from Canada?
U.S. prices can exceed $500 per month. Canadian sources offer savings of 40–70%, especially on generic apixaban.

Do I need a Canadian prescription?
No. Over the Border Meds accepts valid U.S. prescriptions for personal use orders.

Final Thoughts

Trying to save money on Eliquis by splitting tablets is not a safe solution. Instead, talk to your provider about prescribing the correct strength and explore options like ordering generic apixaban from a Canadian pharmacy.

With the right prescription and a referral to a licensed provider, you can stay on the correct dose and reduce your monthly costs—without compromising safety.