Understanding Migraine Treatments: Nurtec, Qulipta, and Ubrelvy

Understanding Migraine Treatments: Nurtec, Qulipta, and Ubrelvy


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Migraines are more than just severe headaches; they can significantly impact daily life. Thankfully, new medications are available to help manage and reduce migraine symptoms. Let’s explore three popular migraine treatments: Nurtec, Qulipta, and Ubrelvy, and discuss why they might be more affordable in Canada.


Nurtec (Rimegepant)

How It Works: Nurtec treats and prevents migraines by blocking a protein called CGRP, which causes migraine pain.

How to Use It: Nurtec is an orally disintegrating tablet that dissolves on your tongue without water. You can take it during a migraine and regularly (every other day) to prevent migraines.

Effectiveness: Many people find relief within an hour, with effects lasting up to 48 hours. Regular use can reduce the number of migraines.

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Qulipta (Atogepant)

How It Works: Qulipta prevents migraines by blocking the CGRP protein, reducing the frequency and severity of migraines.

How to Use It: Qulipta is a daily pill taken to prevent migraines, not to treat them once they’ve started.

Effectiveness: Studies show Qulipta can significantly reduce the number of monthly migraine days, improving quality of life.

Side Effects: Common side effects of Qulipta include nausea, constipation, and fatigue. These side effects are usually mild and manageable.

Weight Changes: Qulipta is not typically associated with significant weight gain or weight loss. However, as with any medication, individual responses can vary.

Migraine Relief: Qulipta is primarily used to prevent migraines rather than to get rid of an active migraine. For treating an active migraine, medications like Nurtec or Ubrelvy might be more appropriate.


Ubrelvy (Ubrogepant)

How It Works: Ubrelvy treats migraines by blocking the CGRP protein to relieve pain.

How to Use It: Ubrelvy is a pill taken at the first sign of a migraine. A second dose can be taken if needed, with at least two hours between doses.

Effectiveness: Ubrelvy can provide relief within two hours, reducing pain and other symptoms like nausea and sensitivity to light and sound.

Side Effects: The most common side effects of Ubrelvy include nausea, tiredness, and dry mouth. These side effects are generally mild and tend to resolve on their own.

Onset of Action: Ubrelvy typically starts working within two hours of taking the medication. Many patients report significant pain relief within this time frame.

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Why These Medications Are Cheaper in Canada

Prescription drug prices in Canada are generally lower than in the United States due to government regulation and negotiation power. The Canadian government regulates drug prices to ensure they remain affordable, and the country’s single-payer healthcare system allows for significant bargaining power with pharmaceutical companies. This results in medications like Nurtec, Qulipta, and Ubrelvy often being more affordable in Canada.

Many Americans take advantage of these lower prices by purchasing their medications from online pharmacies in Canada. This practice helps them save money while still accessing the treatments they need.


Choosing the Right Treatment

Choosing the best migraine treatment depends on how often you get migraines and how well you respond to each medication. Talk to your doctor to find the best plan for you.



  • Nurtec treats and prevents migraines.
  • Qulipta is a daily preventive pill.
  • Ubrelvy provides quick relief from migraine symptoms.


Migraines can be debilitating, but medications like Nurtec, Qulipta, and Ubrelvy offer hope and relief. Understanding how each works can help you and your doctor decide the best treatment plan. Additionally, considering the affordability of these medications in Canada can make managing migraines more accessible. With the right approach, you can manage your migraines and improve your quality of life. Always consult with your healthcare provider to choose the best option for you.