How Jardiance and Farxiga Support Blood Sugar and Heart Health in Diabetes
How Jardiance and Farxiga Support Blood Sugar and Heart Health in Diabetes
- Jason K
Managing Type 2 diabetes often means addressing more than just blood sugar. Many people with diabetes also face a higher risk of heart disease, making it essential to choose treatments that support both blood sugar and heart health. This is where SGLT2 inhibitors like Jardiance and Farxiga come in. These medications not only help control blood sugar but also provide added protection for the heart, making them a valuable choice for certain patients.
What Are SGLT2 Inhibitors?
SGLT2 inhibitors are a class of medications that help lower blood sugar by working with the kidneys. Normally, the kidneys reabsorb sugar from the blood, but SGLT2 inhibitors block this process, causing extra sugar to be removed through urine. This reduces blood sugar levels in a way that’s different from other diabetes medications.
Common SGLT2 Inhibitors include:
- Jardiance (empagliflozin)
- Farxiga (dapagliflozin)
How Do SGLT2 Inhibitors Compare to Other Diabetes Medications?
Compared to other diabetes drugs, SGLT2 inhibitors offer unique benefits for people with heart disease risk:
- Metformin: While effective for blood sugar control, metformin doesn’t have the heart-protective effects of SGLT2 inhibitors.
- Sulfonylureas (e.g., glipizide): These drugs lower blood sugar but can cause hypoglycemia and weight gain, and they don’t offer heart protection.
- DPP-4 Inhibitors (e.g., Januvia): These medications help manage blood sugar but don’t provide heart benefits.
- GLP-1 Receptor Agonists (e.g., Ozempic semaglutide): These are another class of drugs that help with blood sugar and offer heart benefits, but they are usually injected.
How Do SGLT2 Inhibitors Benefit Both Blood Sugar and Heart Health?
1. Lowering Blood Sugar
By blocking sugar reabsorption in the kidneys, SGLT2 inhibitors help lower blood sugar naturally. They don’t rely on insulin to work, so they’re helpful for people who may have insulin resistance. They also have a low risk of causing low blood sugar (hypoglycemia), especially when used alone.
2. Protecting the Heart
One of the main benefits of SGLT2 inhibitors is their impact on heart health. Studies show that Jardiance and Farxiga can reduce the risk of heart failure and heart-related deaths in people with Type 2 diabetes. This is important because people with diabetes are more likely to experience heart disease.
These medications may help the heart by:
- Lowering blood pressure slightly
- Reducing fluid buildup, which helps reduce strain on the heart
- Improving kidney function, which also supports heart health
For these reasons, SGLT2 inhibitors are often recommended for people with diabetes who have a high risk of heart disease.
Why SGLT2 Inhibitors Might Be Recommended
Doctors may recommend SGLT2 inhibitors like Jardiance or Farxiga for people with Type 2 diabetes who have a higher risk of heart disease or kidney problems. Unlike many other diabetes medications, SGLT2 inhibitors lower blood sugar while also protecting the heart, reducing the risk of heart failure and related complications. For patients with both diabetes and heart concerns, this dual benefit makes SGLT2 inhibitors a valuable option.
SGLT2 inhibitors also support weight loss and help protect the kidneys, two important factors for people managing diabetes. By helping the body remove excess glucose, these medications can promote modest weight loss, which supports overall health in diabetes management. Additionally, SGLT2 inhibitors have been shown to protect kidney function, reducing the strain diabetes can place on the kidneys over time. These added benefits make SGLT2 inhibitors a strong choice for patients with complex health needs.
Final Thoughts
SGLT2 inhibitors such as Jardiance and Farxiga are unique in that they not only help control blood sugar but also provide protection for the heart and kidneys. This makes them particularly valuable for people with Type 2 diabetes who are also at risk for cardiovascular issues or kidney complications, both of which are common concerns in diabetes management. By lowering blood sugar levels and reducing strain on the heart and kidneys, these medications offer a well-rounded approach to health.
For people managing multiple health concerns alongside diabetes, SGLT2 inhibitors provide additional benefits that go beyond standard blood sugar control. Their ability to lower blood pressure and support modest weight loss further enhances their value for patients aiming for comprehensive health management. If you’re curious about whether an SGLT2 inhibitor is right for you, speak with your healthcare provider about your options. They can help determine if adding a medication like Jardiance or Farxiga might be beneficial for your health goals.
For more information on diabetes, visit American Diabetes Association’s overview.