Motegrity (Prucalopride) Tablets From Canada

Motegrity, known as Resotran in Canada, is a prescription medication used to treat chronic idiopathic constipation (CIC) in adults. The active ingredient, prucalopride, is a prokinetic agent that helps stimulate bowel movements by enhancing muscle contractions in the intestines, improving bowel function for patients who do not respond to laxatives.

How Motegrity Works

Motegrity works by activating serotonin 5-HT4 receptors in the gastrointestinal tract, which stimulates the smooth muscles of the intestines to contract and promote movement. This action helps restore the body’s natural rhythm for bowel movements, improving overall bowel function and reducing the discomfort associated with chronic constipation.

Motegrity Dosage and Administration

Motegrity is available in tablet form, with the recommended dosage being 2 mg taken once daily, with or without food. In some cases, a lower dose of 1 mg may be prescribed for elderly patients or those with severe kidney impairment. Follow your healthcare provider’s instructions closely, and do not adjust the dose without consulting your doctor.

Motegrity should be taken regularly for the best results. If you miss a dose, take it as soon as you remember unless it is close to the next dose—do not double the dose.

Possible Side Effects of Motegrity

Common side effects of Motegrity include:

• Headache
• Nausea
• Diarrhea
• Abdominal pain

Serious but rare side effects may include:

• Severe allergic reactions
• Severe diarrhea leading to dehydration
• Suicidal thoughts or behavior

Contact your healthcare provider immediately if you experience any severe side effects or notice a worsening of symptoms.

Drug Interactions

Motegrity may interact with certain medications, including:

• Other prokinetic agents
• Medications affecting serotonin levels, such as SSRIs or SNRIs
• Medications that affect kidney function

Always inform your doctor about all medications and supplements you are taking to avoid potential interactions.

Precautions When Using Motegrity

Before starting Motegrity, inform your healthcare provider if you have:

• A history of severe gastrointestinal issues, such as Crohn’s disease or ulcerative colitis
• Kidney problems
• Mental health conditions, including depression or suicidal thoughts

Motegrity should not be used by pregnant or breastfeeding women unless specifically directed by a healthcare provider.

Buying Motegrity from Canada

For U.S. patients, purchasing Motegrity from Canada (where it is known as Resotran) can offer significant savings. Canadian pharmacies often offer lower prices on prescription medications. Follow these tips for safely purchasing Motegrity from Canada:

• Check Pharmacy: Ensure the online Canadian pharmacy is licensed and trustworthy.
• Valid Prescription: You will need a valid U.S. prescription to purchase Motegrity from Canada.
• Consult Your Doctor: Always consult with your healthcare provider before purchasing medications from outside the U.S. to ensure it is safe for you.

Storage Instructions for Motegrity

Store Motegrity tablets at room temperature, between 15°C and 25°C (59°F to 77°F). Keep them away from moisture, heat, and direct light. Ensure the medication is kept out of reach of children and pets.

Frequently Asked Questions (FAQs)

What is Motegrity used for?

Motegrity is used to treat chronic idiopathic constipation in adults. It helps stimulate bowel movements in patients who have not responded well to other treatments, such as laxatives.

Can I buy Motegrity from Canada?

Yes, U.S. patients can purchase Motegrity (known as Resotran in Canada) from licensed Canadian pharmacies. A valid U.S. prescription is required.

How should I take Motegrity?

Take Motegrity exactly as prescribed, typically 2 mg once daily, with or without food. Follow your healthcare provider’s instructions carefully.

Motegrity (Resotran) is an effective treatment for chronic constipation, helping restore regular bowel movements and improving patients' quality of life. If you are considering purchasing Motegrity from Canada, ensure that you buy from a reputable pharmacy and consult with your healthcare provider to make an informed decision.

For more detailed information, you can refer to the official product monograph here.