What is Rexulti?

Rexulti, also known as brexpiprazole, is an antipsychotic medication used to treat mental health conditions like schizophrenia and as an adjunct therapy for major depressive disorder (MDD). It works by modulating dopamine and serotonin receptors in the brain, helping to stabilize mood and improve symptoms of depression and psychosis.

Is Rexulti a Mood Stabilizer?

While Rexulti is not classified as a traditional mood stabilizer, it has mood-stabilizing effects. It helps manage emotional dysregulation in conditions like depression and schizophrenia by balancing neurotransmitter activity. This makes it a valuable option for patients who need additional support beyond standard antidepressants.

How Does Rexulti Work?

Rexulti is a serotonin-dopamine activity modulator (SDAM). It works by acting as a partial agonist at dopamine D2 and serotonin 5-HT1A receptors and as an antagonist at serotonin 5-HT2A receptors. This unique mechanism helps restore balance in neurotransmitter activity, improving mood, cognition, and psychotic symptoms. Its targeted action minimizes side effects compared to older antipsychotics.

Rexulti Benefits

Patients using Rexulti may experience:

• Improved mood and reduced symptoms of depression
• Better management of schizophrenia symptoms, including delusions and hallucinations
• Minimal risk of weight gain compared to other antipsychotics
• Fewer side effects due to its selective receptor activity

Does Rexulti Help with Depression?

Yes, Rexulti is approved as an adjunctive treatment for major depressive disorder. When combined with standard antidepressants, it helps alleviate persistent depressive symptoms such as low energy, feelings of hopelessness, and difficulty concentrating. Many patients report significant improvements in their overall quality of life.

Dosage and Administration

Rexulti is available in various strengths, ranging from 0.25 mg to 4 mg tablets. The typical starting dose for adjunctive treatment in depression is 0.5 mg to 1 mg daily, which may be titrated up to a maximum dose of 3 mg daily. For schizophrenia, the usual dose ranges from 1 mg to 4 mg daily. Always follow your healthcare provider's instructions for dosing and frequency.

Common Side Effects

Like all medications, Rexulti may cause side effects. Common side effects include:

• Weight gain
• Restlessness or agitation
• Headache
• Fatigue
• Increased appetite

If side effects persist or worsen, contact your healthcare provider immediately.

Contraindications

Rexulti is not suitable for everyone. Contraindications include:

• Known hypersensitivity to brexpiprazole or any of its ingredients
• History of severe allergic reactions to antipsychotic medications
• Severe liver or kidney impairment without dosage adjustment

Always consult with your healthcare provider before starting Rexulti to ensure it is safe for you.

Use in Pregnancy and Breastfeeding

Rexulti should only be used during pregnancy if the potential benefits outweigh the risks. There is limited data on its use in pregnant women, but animal studies suggest potential risks to the fetus. Pregnant women taking Rexulti should be closely monitored.

It is unknown whether brexpiprazole is excreted in human breast milk. Breastfeeding mothers should consider the potential risks and benefits before using Rexulti. Consult your doctor for personalized guidance.

Common Drug Interactions

Rexulti can interact with certain medications, including:

• Strong CYP3A4 inhibitors (e.g., ketoconazole) or inducers (e.g., rifampin), which may affect drug metabolism
• Antidepressants, which may increase the risk of serotonin syndrome
• Other antipsychotics, which may enhance side effects

Inform your healthcare provider about all medications and supplements you are taking to avoid harmful interactions.

Foods to Avoid

While taking Rexulti, it is recommended to:

• Avoid excessive alcohol consumption, as it may enhance drowsiness and dizziness.
• Limit high-fat meals, which can delay absorption of the medication.

Maintaining a balanced diet can help reduce side effects like weight gain and ensure the medication works effectively.

Rexulti Coupon and Savings

Looking to save on Rexulti? Many Canadian pharmacies offer Rexulti coupon codes, such as hello10, to provide a 10% discount on your first order. These discounts make it more affordable for American patients to access this effective treatment. Check with your pharmacy for additional promotions and savings opportunities.

Why Buy Rexulti from Canada?

Many Americans choose to buy Rexulti or buy brexpiprazole from Canada due to the significant cost savings. Canadian pharmacies offer regulated pricing, ensuring the same high-quality medication at a fraction of U.S. prices. Purchasing from licensed Canadian pharmacies helps patients manage their healthcare expenses without compromising on treatment efficacy.

Alternatives to Rexulti

If Rexulti is not suitable for you, other options include:

• Abilify (aripiprazole): Another SDAM with similar indications
• Latuda (lurasidone): Often used for bipolar depression and schizophrenia
• Seroquel (quetiapine): Commonly prescribed for mood stabilization

Consult your healthcare provider to determine which medication is best suited for your needs.

Storage and Stability

Store Rexulti at room temperature (15°C to 30°C) in its original packaging to protect it from light and moisture. Keep out of reach of children and pets.