JANUMET XR from Canada

JANUMET® is a medication that combines two active ingredients: sitagliptin and metformin hydrochloride. It is used to help control blood sugar levels in adults with type 2 diabetes, especially when other treatments are not working well enough on their own.

Available Dosages

JANUMET® comes in various dosages to fit different treatment needs:

JANUMET® Tablets:

• 50 mg sitagliptin / 500 mg metformin hydrochloride
• 50 mg sitagliptin / 850 mg metformin hydrochloride
• 50 mg sitagliptin / 1000 mg metformin hydrochloride

JANUMET® XR (Extended Release) Tablets:

• 50 mg sitagliptin / 500 mg metformin hydrochloride
• 50 mg sitagliptin / 1000 mg metformin hydrochloride
• 100 mg sitagliptin / 1000 mg metformin hydrochloride

How to Take JANUMET®

JANUMET® Tablets: Usually taken twice a day with meals to reduce stomach upset.

JANUMET® XR Tablets: Taken once a day with an evening meal. Do not crush or chew the tablets; swallow them whole.

Side Effects

While JANUMET® is generally well tolerated, it can cause some side effects. Common side effects include:

• Gastrointestinal Issues: Diarrhea, nausea, vomiting, and stomach upset.
• Low Blood Sugar (Hypoglycemia): Especially when used with other diabetes medications like insulin or sulfonylureas.
• Upper Respiratory Infections: Such as the common cold.
• Headache: Mild to moderate in intensity.
• Taste Changes: Some patients report a metallic taste.

Serious but rare side effects include:

• Lactic Acidosis: A serious condition due to metformin accumulation. Symptoms include muscle pain, difficulty breathing, stomach pain, dizziness, and feeling cold.
• Pancreatitis: Inflammation of the pancreas. Symptoms include severe stomach pain, nausea, and vomiting.

Drug Interactions

JANUMET® can interact with other medications, which may increase the risk of side effects or affect how well JANUMET® works. Inform your doctor if you are taking:

• Insulin or Sulfonylureas: Increases risk of low blood sugar.
• Diuretics (Water Pills): Can affect kidney function.
• Cationic Drugs: Such as cimetidine, which can increase metformin levels.
• Alcohol: Increases the risk of lactic acidosis.
• Radiological Contrast Agents: Used in some imaging procedures can affect kidney function.

Saving Money by Buying JANUMET from Canada

If you live in the U.S., you can save money on JANUMET® by purchasing it from Canada. Here’s how:

1. Consult Your Doctor: Make sure your doctor approves buying JANUMET and get a US prescription if needed.
2. Find a Canadian Pharmacy: Look for online pharmacies that are verified and have good reviews.
3. Compare Prices: Check the prices on different websites to ensure you’re getting the best deal on JANUMET®.
4. Place Your Order: Follow the pharmacy’s instructions to place your order. You may need to provide your prescription.
5. Shipping and Delivery: Be aware of the shipping times and ensure your JANUMET® will arrive before you run out.

Coupons and Discounts

In Canada, many pharmacies offer coupons or discounts for JANUMET®. Here are some tips to find and use them:

1. Check Pharmacy Websites: Many pharmacies list their discounts and coupon offers online.
2. Sign Up for Newsletters: Some pharmacies send exclusive discounts to their subscribers.
3. Ask Your Doctor: Sometimes, healthcare providers have access to discount programs or samples.
4. Use Discount Cards: Look for discount cards that can be used at participating pharmacies.

Additional Information

For more detailed information on JANUMET®, including side effects, precautions, and clinical trial results, you can refer to the Product Monograph.

If you have any questions about your medication or how to purchase it, consult with your healthcare provider.